产品货号：
Z36915
中文名称：
IDH1抗体
英文名称：
Anti-IDH1 Antibody (Clone#16H7)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IDH1 Antibody (Clone#16H7) |
| 指标别名 | IDCD;IDH;IDH1;IDP;IDPC;NADP(+) specific ICDH;Oxalosuccinate decarboxylase;PICD |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM |
| 基因名称 | IDH1 |
| 克隆号 | 16H7 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human IDH1 (381-413aa KGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK),different from the related mouse and rat sequences by one amino acid. |
| 实际分子量 | 47KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Isocitrate dehydrogenase 1 (NADP+),soluble is an enzyme that in humans is encoded by the IDH1 gene.Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate.These enzymes belong to two distinct subclasses,one of which utilizes NAD(+) as the electron acceptor and the other NADP(+).Five isocitrate dehydrogenases have been reported:three NAD(+)-dependent isocitrate dehydrogenases,which localize to the mitochondrial matrix,and two NADP(+)-dependent isocitrate dehydrogenases,one of which is mitochondrial and the other predominantly cytosolic.Each NADP(+)-dependent isozyme is a homodimer.The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes.It contains the PTS-1 peroxisomal targeting signal sequence.The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions,such as the conversion of 2,4-dienoyl-CoAs to 3-enoyl-CoAs,as well as in peroxisomal reactions that consume 2-oxoglutarate,namely the alpha-hydroxylation of phytanic acid.The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Uniprot ID | O75874 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | isocitrate dehydrogenase 1 (NADP+),soluble |
| 蛋白名全称 | Isocitrate dehydrogenase [NADP] cytoplasmic |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
相关搜索：IDH1抗体，IDH1单抗，Anti-IDH1 Antibody (Clone#16H7)